9OU9

AZD3759 in complex with wild-type EGFR

This is a non-PDB format compatible entry.

Summary for 9OU9

• Entry DOI: 10.2210/pdb9ou9/pdb
• Descriptor: Epidermal growth factor receptor, 4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl (2R)-2,4-dimethylpiperazine-1-carboxylate (3 entities in total)
• Functional Keywords: cancer, drug discovery, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37764.03

Authors

Lantry, A.M.,Damnghani, T.,Heppner, D.E. (deposition date: 2025-05-28, release date: 2025-12-10)

• Primary citation: Lantry, A.M.,Damghani, T.,Heppner, D.E.; Structural and functional studies of covalent EGFR inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)