9OT4

SARS-CoV-2 Main Protease (Mpro) in Complex with Covalent Inhibitor E9

This is a non-PDB format compatible entry.

Summary for 9OT4

• Entry DOI: 10.2210/pdb9ot4/pdb
• Descriptor: 3C-like proteinase nsp5, 1-(8-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)ethan-1-one (3 entities in total)
• Functional Keywords: viral, covalent, inhibitor, protease, viral protein, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68107.67

Authors

Mazzorana, M.,Oliveira Borges, P.H.,Silva-Junior, F.,Baptista Ferreira, S.,Walsh, M.A. (deposition date: 2025-05-26, release date: 2026-06-24)

• Primary citation: Mazzorana, M.,Oliveira Borges, P.H.,Silva-Junior, F.,Baptista Ferreira, S.,Walsh, M.A.; SARS-CoV-2 Main Protease (Mpro) in Complex with Covalent Inhibitor E2; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)