9OSL

Crystal structure of the transpeptidase domain of a Y422A mutant of PBP2 from Neisseria gonorrhoeae strain H041 acylated by ceftriaxone

Summary for 9OSL

• Entry DOI: 10.2210/pdb9osl/pdb
• Descriptor: Probable peptidoglycan D,D-transpeptidase PenA, CEFOTAXIME, C3' cleaved, open, bound form, TRIETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: penicillin-binding protein, peptidoglycan transpeptidase, ceftriaxone, ligase
• Biological source: Neisseria gonorrhoeae
• Total number of polymer chains: 1
• Total formula weight: 35909.09

Authors

Stratton, C.M.,Bala, S.,Davies, C. (deposition date: 2025-05-24, release date: 2026-06-03)

• Primary citation: Stratton, C.M.,Bala, S.,Bivins, M.M.,Nicholas, R.A.,Davies, C.; Tyrosine-422 plays a crucial role in acylation and transpeptidation in penicillin-binding protein 2 from Neisseria gonorrhoeae; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)