9OOK

Cryo-EM structure of vaccine-elicited antibody T3_QB_G12 in complex with HIV Env trimer Q23-APEX-GT1

Summary for 9OOK

• Entry DOI: 10.2210/pdb9ook/pdb
• EMDB information: 70664
• Descriptor: T3_QB_G12 heavy chain, T3_QB_G12 light chain, HIV Env gp120, ... (8 entities in total)
• Functional Keywords: immune complex, neutralizing antibody, v2 apex, mouse model, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 12
• Total formula weight: 394753.12

Authors

Roark, R.S.,Shapiro, L.S.,Kwong, P.D. (deposition date: 2025-05-15, release date: 2025-11-05)

• Primary citation: Amrit, G.,Roark, R.S.,Kwong, P.D.,Batista, F.D.; Rapid acquisition of HIV-1 neutralization breadth in a rhesus V2 apex germline antibody mouse model with a single bolus priming immunization; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.8 Å)