9OEG

Structure of the human astrovirus VA1 capsid spike bound to antibody 2A2

Summary for 9OEG

• Entry DOI: 10.2210/pdb9oeg/pdb
• EMDB information: 70398
• Descriptor: 2A2 heavy chain, 2A2 light chain, Capsid polyprotein VP90 (3 entities in total)
• Functional Keywords: astrovirus, neutralizing antibody, epitope mapping, neurovirulent., viral protein
• Biological source: Astrovirus VA1; More
• Total number of polymer chains: 6
• Total formula weight: 159943.07

Authors

Ghosh, A.,Dzimianski, J.V.,Balasco Serrao, V.H.,DuBois, R.M. (deposition date: 2025-04-28, release date: 2026-07-08)

• Primary citation: Ghosh, A.,Dzimianski, J.V.,Lopez, T.,Espinosa, R.,Balasco Serrao, V.H.,Arias, C.F.,DuBois, R.M.; Cryo-EM Structures of the Human Astrovirus VA1 Capsid Spike Bound to Neutralizing Antibodies: Implications for Therapeutic Strategies; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.05 Å)