9OCM

Crystal structure of dihydroorotate dehydrogenase from Leishmania brasiliensis in complex with (E)-5-(3-(4-nitrophenyl)allylidene)pyrimidine-2,4,6(1H,3H,5H)-trione

This is a non-PDB format compatible entry.

Summary for 9OCM

• Entry DOI: 10.2210/pdb9ocm/pdb
• Descriptor: Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, DIMETHYL SULFOXIDE, ... (7 entities in total)
• Functional Keywords: covalent inhibitor, dhodh, oxireductase, oxidoreductase
• Biological source: Leishmania braziliensis
• Total number of polymer chains: 2
• Total formula weight: 76749.14

Authors

Vaidergorn, M.M.,Nonato, M.C.,Froes, T.Q.,Augusto, B.S. (deposition date: 2025-04-24, release date: 2026-05-06)

• Primary citation: Vaidergorn, M.M.,Nonato, M.C.,Froes, T.Q.,Augusto, B.S.; Crystal structure of dihydroorotate dehydrogenase from Leishmania brasiliensis in complex with (E)-5-(3-(4-nitrophenyl)allylidene)pyrimidine-2,4,6(1H,3H,5H)-trione; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.97 Å)