9OA9

CryoEM structure of anti-MHC-I mAb B1.23.2 Fc domains

Summary for 9OA9

• Entry DOI: 10.2210/pdb9oa9/pdb
• EMDB information: 46601 46602 70276
• Descriptor: Anti-MHC-I mAb B1.23.2 Fc domains H-chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: mhc-i, hla, anti-human-mab, h2-dd, b1.23.2, anti-mhc-i antibody, anti-tumor, cancer immunotherapy, antitumor protein
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 99240.92

Authors

Jiang, J.,Natarajan, K.,Margulies, D.H. (deposition date: 2025-04-20, release date: 2026-02-04)

• Primary citation: Jiang, J.,Natarajan, K.,Margulies, D.H.; CryoEM structure of anti-MHC-I B1.23.2 Fc domains; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.44 Å)