9O8E

amyloid fibril of recombinant full-length 2N4R tau complexed with unfractionated mouse liver RNA and seeded by Alzheimer's disease tau fibrils

Summary for 9O8E

• Entry DOI: 10.2210/pdb9o8e/pdb
• EMDB information: 70224
• Descriptor: Isoform Tau-F of Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: amyloid fibril, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 5
• Total formula weight: 234955.06

Authors

Jiang, Y.X.,Sawaya, M.R.,Abskharon, R.,Ge, P.,Boyer, D.R.,Eisenberg, D.S. (deposition date: 2025-04-15, release date: 2026-03-18)

• Primary citation: Abskharon, R.,Jiang, Y.X.,Ge, P.,Sawaya, M.R.,Zhang, J.,Boyer, D.R.,Dolinsky, J.L.,Cascio, D.,Guo, F.,Eisenberg, D.S.; RNA contributes to polymorphism of tau amyloid fibrils; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)