9O7F

CHIP E3 ligase dimer in Symmetric state bound to 2 Fab H1

Summary for 9O7F

Entry DOI	10.2210/pdb9o7f/pdb
EMDB information	70197
Descriptor	E3 ubiquitin-protein ligase CHIP, H1 Fab heavy chain, H1 Fab light chain (3 entities in total)
Functional Keywords	u-box e3 ligase, fab, cryo-em, protein degradation, ligase-immune system complex, ligase/immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	157738.29
Authors	Unnikrishnan, A.,Southworth, D. (deposition date: 2025-04-15, release date: 2026-05-13)
Primary citation	Unnikrishnan, A.,Southworth, D. Fab H1-bound CHIP E3 ligase dimer in Symmetric state To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation