9O6V

Recombinant AD PHF complexed with SW-MK-NBD (PHF2)

This is a non-PDB format compatible entry.

Summary for 9O6V

• Entry DOI: 10.2210/pdb9o6v/pdb
• EMDB information: 70182
• Descriptor: Microtubule-associated protein tau, 7-nitro-N-[2-(2-{[(3P)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-7-yl]oxy}ethoxy)ethyl]-2,1,3-benzoxadiazol-4-amine (2 entities in total)
• Functional Keywords: mk-6240 pet ligand, ad phf, protein fibril, sw-mk-nbd, amyloid dye
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 10
• Total formula weight: 86959.01

Authors

Kunach, P.,Diamond, M.I. (deposition date: 2025-04-14, release date: 2026-04-22)

• Primary citation: Kunach, P.,Diamond, M.I.; Development of a tau amyloid dye from a PET ligand; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.72 Å)