9O6R

Co-crystal structure of caPCNA bound to the AOH1996 derivative, AOH2.29-LE

Summary for 9O6R

• Entry DOI: 10.2210/pdb9o6r/pdb
• Descriptor: Proliferating cell nuclear antigen, N-{2-[(4-methylphenyl)sulfanyl]phenyl}-N~2~-(naphthalene-1-carbonyl)-L-alpha-glutamine, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: proliferating cell nuclear antigen, complex, aoh1996, aoh1160, dna binding protein, aoh1996 analog, aoh2.29-le
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 118458.19

Authors

Jossart, J.,Perry, J.J. (deposition date: 2025-04-14, release date: 2026-07-15)

• Primary citation: Haratipour, P.,Zangi, M.,Gu, L.,Li, C.M.,Yaghoubi, M.,Jossart, J.,Lingeman, R.G.,Aris, K.L.,Wendel, S.,Meng, F.,Xia, F.,Azmi, A.S.,Synold, T.W.,Raoof, M.,Wallace, N.,Perry, J.J.P.,Malkas, L.H.,Hickey, R.J.; Second-Generation AOH1996 Analogues with Enhanced Pharmacological Properties for Targeting PCNA; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.87 Å)