9O5F

Crystal Structure of EgtUC binding domain double mutant I243P T274G bound to L-Ergothioneine from S. pneumoniae

Summary for 9O5F

Entry DOI	10.2210/pdb9o5f/pdb
Descriptor	Ergothioneine transporter EgtUC, trimethyl-[(2S)-1-oxidanyl-1-oxidanylidene-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propan-2-yl]azanium, CITRATE ANION, ... (6 entities in total)
Functional Keywords	l-ergothioneine, abc transporter, s. pneumoniae, transport protein
Biological source	Streptococcus pneumoniae D39
Total number of polymer chains	1
Total formula weight	31567.54
Authors	Legg, K.A.,Gonzalez-Gutierrez, G.,Giedroc, D.P. (deposition date: 2025-04-10, release date: 2026-01-14)
Primary citation	Legg, K.A.,Gonzalez-Gutierrez, G.,Edmonds, K.A.,Shushkov, P.G.,Giedroc, D.P. C-H...S hydrogen bonds are essential for molecular recognition of ergothioneine by the bacterial ergothioneine transporter EgtUC in Streptococcus pneumoniae. To Be Published,
Experimental method	X-RAY DIFFRACTION (1.36 Å)

Structure validation