9O51
Cryo-EM structure of the human SK2-4 chimera/calmodulin channel complex in the Ca2+ free state
Summary for 9O51
| Entry DOI | 10.2210/pdb9o51/pdb |
| Related | 9O48 |
| EMDB information | 70120 |
| Descriptor | Intermediate conductance calcium-activated potassium channel protein 4,Small conductance calcium-activated potassium channel protein 2 chimera, Calmodulin-1, POTASSIUM ION, ... (4 entities in total) |
| Functional Keywords | ion channel, calcium, potassium, calmodulin, transport protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 8 |
| Total formula weight | 265177.34 |
| Authors | Cassell, S.J.,Khoshouei, M.,Wilhelm, W.A.,Whicher, J.R. (deposition date: 2025-04-09, release date: 2025-07-09) |
| Primary citation | Cassell, S.J.,Li, W.,Krautwald, S.,Khoshouei, M.,Lee, Y.T.,Hou, J.,Guan, W.,Peukert, S.,Wilhelm, W.A.,Whicher, J.R. Mechanism of SK2 channel gating and its modulation by the bee toxin apamin and small molecules To Be Published, |
| Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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