9O0L

CryoEM structure of the CCDC6-PP2Ac multimer

Summary for 9O0L

• Entry DOI: 10.2210/pdb9o0l/pdb
• EMDB information: 49992
• Descriptor: Coiled-coil domain-containing protein 6, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, MANGANESE (II) ION (3 entities in total)
• Functional Keywords: phosphatase, scaffolding, coiled-coil, structural protein, structural protein-hydrolase complex, structural protein/hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 392701.99

Authors

Hsu, P.L.,Michaelian, N.,Azumaya, C.,Coassolo, S.,Yauch, R.L. (deposition date: 2025-04-02, release date: 2026-01-21)

• Primary citation: Hsu, P.L.,Michaelian, N.,Azumaya, C.,Coassolo, S.,Yauch, R.L.,Maculins, T.,Dimitrova, Y.; The SCFFBXO42-CCDC6 axis regulates proteosomal degradation of the catalytic subunit of PP2A; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.5 Å)