9NW0

Cryo-EM structure of rhesus antibody CH42-Apex1.01 in complex with HIV Env trimer Q23-APEX-GT2

Summary for 9NW0

• Entry DOI: 10.2210/pdb9nw0/pdb
• EMDB information: 49870
• Descriptor: CH42-Apex1.01 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, CH42-Apex1.01 kappa chain, ... (10 entities in total)
• Functional Keywords: immune complex, neutralization, v2 apex, germline-targeting, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Macaca mulatta; More
• Total number of polymer chains: 8
• Total formula weight: 288289.58

Authors

Roark, R.S.,Shapiro, L.S.,Kwong, P.D. (deposition date: 2025-03-21, release date: 2026-04-01)

• Primary citation: Mishra, N.,Roark, R.S.,Kwong, P.D.,Shaw, G.M.,Andrabi, R.; Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)