9NVW

Cryo-EM structure of rhesus antibody CH35-Apex1.08 in complex with HIV Env trimer Q23-APEX-GT2

Summary for 9NVW

• Entry DOI: 10.2210/pdb9nvw/pdb
• EMDB information: 49866
• Descriptor: CH35-Apex1.08 heavy chain, CH35-Apex1.08 kappa chain, HIV envelope gp120, ... (9 entities in total)
• Functional Keywords: immune complex, neutralization, v2 apex, viral protein, germline-targeting, viral protein-immune system complex, viral protein/immune system
• Biological source: Macaca mulatta; More
• Total number of polymer chains: 8
• Total formula weight: 288135.39

Authors

Roark, R.S.,Shapiro, L.S.,Kwong, P.D. (deposition date: 2025-03-21, release date: 2026-04-01)

• Primary citation: Mishra, N.,Roark, R.S.,Kwong, P.D.,Shaw, G.M.,Andrabi, R.; Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)