9NVV

Cryo-EM structure of V2 apex germline-targeting HIV Env trimer Q23-APEX-GT2

Summary for 9NVV

• Entry DOI: 10.2210/pdb9nvv/pdb
• EMDB information: 49865
• Descriptor: HIV envelope gp120, HIV envelope gp41 ectodomain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: hiv, viral protein, germline-targeting, immunogen, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 332394.35

Authors

Roark, R.S.,Shapiro, L.S.,Kwong, P.D. (deposition date: 2025-03-21, release date: 2026-04-01)

• Primary citation: Mishra, N.,Roark, R.S.,Kwong, P.D.,Shaw, G.M.,Andrabi, R.; Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)