9NT7

Cryo-EM structure of cpd2-GLP-1(9-36)-GLP_1R-Gs complex

This is a non-PDB format compatible entry.

Summary for 9NT7

• Entry DOI: 10.2210/pdb9nt7/pdb
• EMDB information: 49754
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: cryo-em, gpcr, glp-1r, cpd2, positive allosteric modulator, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 164684.36

Authors

Zhang, X.,Belousoff, M.J.,Sexton, P.M.,Wootten, D. (deposition date: 2025-03-18, release date: 2026-09-30)

• Primary citation: Zhang, X.,Belousoff, M.J.,Sexton, P.M.,Wootten, D.; cryo-EM structure of cpd2-GLP-1(9-36)-GLP_1R-Gs complex; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.5 Å)