9NSR

Crystal structure of bifunctional farnesyl/geranylgeranyl pyrophosphate synthase (FPPS/GGPPS) from Plasmodium falciparum in complex with MMV019313

This is a non-PDB format compatible entry.

Summary for 9NSR

• Entry DOI: 10.2210/pdb9nsr/pdb
• Descriptor: Bifunctional farnesyl/geranylgeranyl diphosphate synthase, N-[3-(azepan-1-yl)propyl]-5-methyl-4-oxo-4,5-dihydrothieno[3,2-c]quinoline-2-carboxamide (2 entities in total)
• Functional Keywords: ssgcid, structural genomics, seattle structural genomics center for infectious disease, geranylgeranyl pyrophosphate synthase, transferase
• Biological source: Plasmodium falciparum 3D7
• Total number of polymer chains: 1
• Total formula weight: 45066.44

Authors

Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2025-03-17, release date: 2025-03-26)

• Primary citation: Lovell, S.,Cooper, A.,Liu, L.,Battaile, K.P.; Crystal structure of bifunctional farnesyl/geranylgeranyl pyrophosphate synthase (FPPS/GGPPS) from Plasmodium falciparum in complex with MMV019313; To be published,

Experimental method

X-RAY DIFFRACTION (3.25 Å)