9NSP

MPXV replisome bound to ssDNA

Summary for 9NSP

• Entry DOI: 10.2210/pdb9nsp/pdb
• EMDB information: 49747
• Descriptor: Uncoating factor OPG117, DNA polymerase, DNA polymerase processivity factor component OPG148, ... (6 entities in total)
• Functional Keywords: mpxv, replisome, replication, viral protein, viral protein-dna complex, viral protein/dna
• Biological source: Monkeypox virus; More
• Total number of polymer chains: 10
• Total formula weight: 743124.84

Authors

Yu, Z.,Abraham, J. (deposition date: 2025-03-17, release date: 2026-09-02)

• Primary citation: Yu, Z.,Sathyanarayana, P.,Tan, J.M.J.T.,Hu, S.,Fan, X.,Gao, A.,Kranzusch, P.J.,Loparo, J.J.,Abraham, J.; Structure and operating principles of a monkeypox virus replisome; Nature, 2026; DOI: 10.1038/s41586-026-10937-2

Experimental method

ELECTRON MICROSCOPY (4.1 Å)