9NSI

Cryo-EM structure of GLP-1R-Gs complex with GLP-1 (9-36) and cpd19

This is a non-PDB format compatible entry.

Summary for 9NSI

• Entry DOI: 10.2210/pdb9nsi/pdb
• EMDB information: 49746
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• Functional Keywords: cryo-em, gpcr, glp-1r, complex, positive allosteric modulator, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 164921.75

Authors

Zhang, X.,Belousoff, M.J.,Wootten, D.,Patrick, P.M. (deposition date: 2025-03-17, release date: 2026-09-30)

• Primary citation: Zhang, X.,Belousoff, M.J.,Wootten, D.,Patrick, P.M.; Cryo-EM structure of GLP-1R-Gs complex with GLP-1 (9-36) and cpd19; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.2 Å)