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9NP6

Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and blunt end DNA

Summary for 9NP6
Entry DOI10.2210/pdb9np6/pdb
Related6PPJ 6PPR 6PPU 7SJR
EMDB information49626
DescriptorDNA 3'-5' helicase, DNA (30-MER), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
Functional Keywordsatpase, helicase, dna, isomerase-dna complex, isomerase/dna
Biological sourceMycolicibacterium smegmatis MC2 155
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Total number of polymer chains3
Total formula weight248547.83
Authors
Warren, G.M.,De la Cruz, M.J.,Goldgur, Y.,Shuman, S. (deposition date: 2025-03-11, release date: 2025-03-19)
Primary citationWarren, G.M.,De la Cruz, M.J.,Goldgur, Y.,Meir, A.,Greene, E.C.,Shuman, S.
Structure of an initiation complex mycobacterial helicase-nuclease AdnAB at a blunt double-strand break reveals locl melting that engages the 3' tracking strand at the ratchet pawl of the helicase motor
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.4 Å)
Structure validation

247536

PDB entries from 2026-01-14

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