9NP0

Structure of human annexin A1 in complex with 2C1 Fab

Summary for 9NP0

• Entry DOI: 10.2210/pdb9np0/pdb
• EMDB information: 49625
• Descriptor: Annexin A1, 2C1 Fab heavy chain, 2C1 Fab light chain (3 entities in total)
• Functional Keywords: annexin a1, anxa1, anti-annexin a1 antibody, fab, protein binding, protein binding-immune system complex, protein binding/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 86852.63

Authors

Nadezhdin, K.D.,Sobolevsky, A.I. (deposition date: 2025-03-10, release date: 2026-04-01)

• Primary citation: Nadezhdin, K.D.,Sovolevsky, A.I.; Annexin A1 plays an essential dual role throughout neoplastic progression by stimulating tumor growth and modulating immune microenvironment via direct binding of beta-catenin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.32 Å)