9NNV

X-ray structure of CCoV-HuPn-2018 main protease bound to non-covalent inhibitor X77 at 2.15A

Summary for 9NNV

• Entry DOI: 10.2210/pdb9nnv/pdb
• Descriptor: 3C-like proteinase, N-(4-tert-butylphenyl)-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-1H-imidazole-4-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: main protease, 3-chymotrypsin-like protease, mpro, 3clpro, structural genomics, center for structural biology of infectious diseases, csbid, viral protein, viral protein-hydrolase complex, viral protein/hydrolase
• Biological source: Canine coronavirus
• Total number of polymer chains: 2
• Total formula weight: 67466.39

Authors

Jayashankar, U.,Ghosh, A.K.,Mesecar, A.D.,Center for Structural Biology of Infectious Diseases (CSBID) (deposition date: 2025-03-06, release date: 2026-09-09)

• Primary citation: Jayashankar, U.,Ghosh, A.K.,Mesecar, A.D.; X-ray structure of CCoV-HuPn-2018 main protease bound to non-covalent inhibitor X77 at 2.15A; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.15 Å)