9NF8

Cryo-EM structure of Ro60/La/truncated misfolded human pre-5S rRNA complex with Fab, composite map

Summary for 9NF8

Entry DOI	10.2210/pdb9nf8/pdb
EMDB information	49355
Descriptor	RNA-binding protein RO60, Lupus La protein, Truncated misfolded pre-5S rRNA (3 entities in total)
Functional Keywords	ro60 autoantigen, rna chaperone, rna folding, la autoantigen, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	134926.13
Authors	Nam, H.,Deme, J.C.,Lea, S.M.,Wolin, S.L. (deposition date: 2025-02-21, release date: 2026-02-04)
Primary citation	Nam, H.,Deme, J.C.,Sim, S.,Boccitto, M.,Lea, S.M.,Wolin, S.L. Mechanistic insights into RNA chaperoning by Ro60 and La autoantigens Cell(Cambridge,Mass.), 2026 Cited by DOI: 10.1016/j.cell.2025.12.030 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation