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9NCO

IN-ML-15 bound to IGF1Rzip

Summary for 9NCO
Entry DOI10.2210/pdb9nco/pdb
EMDB information49261
DescriptorInsulin-like growth factor 1 receptor, IN-ML-15 beta, IN-ML-15 alpha (3 entities in total)
Functional Keywordsigf receptor, insulin-like growth factor, insulin, igf, signaling protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight210364.97
Authors
Kirk, N.S. (deposition date: 2025-02-16, release date: 2026-02-18)
Primary citationSelicharova, I.,Kirk, N.S.,Lubos, M.,Kertisova, A.,Mitrova, K.,Zakova, L.,Chrudinova, M.,Brezinova, J.,Harant, K.,Voldrich, J.,Panikova, T.,Torres-Aleman, I.,Huffman, D.,Jiracek, J.
Neuroprotective potential of an engineered hormone with dual insulin and IGF-1 receptor activity
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.4 Å)
Structure validation

249697

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