9NCG
Marpharsen treated Treponema pallidum thioredoxin strain Nichols
Summary for 9NCG
| Entry DOI | 10.2210/pdb9ncg/pdb |
| Related | 9NCE |
| Descriptor | Thioredoxin, 3-HYDROXY-PROPANOIC ACID (3 entities in total) |
| Functional Keywords | salvarsan, mapharsen, arsenic, thioredoxin, thioredoxin reductase, structural protein |
| Biological source | Treponema pallidum subsp. pallidum str. Nichols |
| Total number of polymer chains | 1 |
| Total formula weight | 15507.61 |
| Authors | Carbone, V.,Ronimus, R.S.,Sutherland-Smith, A.J. (deposition date: 2025-02-16, release date: 2026-02-11) |
| Primary citation | Carbone, V.,Ronimus, R.S.,Sutherland-Smith, A.J. Structural examination of thioredoxin and thioredoxin reductase from the syphilis organism Treponema pallidum with Mapharsen, the active ingredient of the original magic bullet (Salvarsan). To Be Published, |
| Experimental method | X-RAY DIFFRACTION (2.64 Å) |
Structure validation
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