9N9T

Crystal structure of Main protease of PEDV in complex with AVI8122

This is a non-PDB format compatible entry.

Summary for 9N9T

• Entry DOI: 10.2210/pdb9n9t/pdb
• Descriptor: Nsp5, N-[(2S)-3-cyclopropyl-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopiperidin-3-yl]butan-2-yl}amino)-1-oxopropan-2-yl]-7-fluoro-1H-indole-2-carboxamide (3 entities in total)
• Functional Keywords: main protease, nsp5, pedv, inhibitor, avi8122, viral protein
• Biological source: Porcine epidemic diarrhea virus
• Total number of polymer chains: 2
• Total formula weight: 66593.37

Authors

Chen, P.,Lu, J.,Lemieux, M.J. (deposition date: 2025-02-11, release date: 2026-02-18)

• Primary citation: Chen, P.,Lu, J.,Lemieux, M.J.; Identification of Inhibitors Broadly Against Main Proteases of coronavirus; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)