9N99

SARS-CoV-2 Main protease in complex with AVI-8122

This is a non-PDB format compatible entry.

Summary for 9N99

• Entry DOI: 10.2210/pdb9n99/pdb
• Descriptor: 3C-like proteinase nsp5, N-[(2S)-3-cyclopropyl-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopiperidin-3-yl]butan-2-yl}amino)-1-oxopropan-2-yl]-7-fluoro-1H-indole-2-carboxamide (3 entities in total)
• Functional Keywords: sars-cov-2, main protease, nsp5, 3cl, inhibitor, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68600.14

Authors

Chen, P.,Lu, J.,Lemieux, M.J. (deposition date: 2025-02-10, release date: 2026-02-18)

• Primary citation: Chen, P.,Lu, J.,Lemieux, M.J.; Identification of Inhibitors Broadly Against Proteases of Coronaviruses; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)