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9N7S

H1 hemagglutinin (A/California/04/2009) with E47K mutation in HA2 in complex with central stem-targeting Fab ST10

Summary for 9N7S
Entry DOI10.2210/pdb9n7s/pdb
EMDB information49098
DescriptorH1 HA2, ST10 Light Chain Fab, H1 HA1, ... (8 entities in total)
Functional Keywordsinfluenza, hemagglutinin, h1, monoclonal, complex, fab complex, viral fusion protein, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceInfluenza A virus
More
Total number of polymer chains8
Total formula weight223496.64
Authors
Brouwer, P.J.M.,Loeffler, J.R.,Ferguson, J.A.,Rodriguez, A.J.,Han, J.,Ward, A.B. (deposition date: 2025-02-06, release date: 2026-02-18)
Primary citationFisher, A.,Corcoran, M.,Chernyshev, M.,Brouwer, P.J.M.,Gillespie, R.,Nicoletto, A.,Loeffler, J.R.,Ferguson, J.A.,Rodriguez, A.J.,Narang, S.,Adori, M.,Angeletti, D.,van Gils, M.J.,Castro Dopico, X.,Kanekiyo, M.,Ward, A.B.,Han, J.,Karlsson Hedestam, G.B.
Individualized IG genotyping coupled with high throughput isolation of influenza HA-specific monoclonal antibodies
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.97 Å)
Structure validation

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