9N5R

X-ray structure of CCoV-HuPn-2018 main protease covalently bound to inhibitor GRL-170-21 at 1.89A

This is a non-PDB format compatible entry.

Summary for 9N5R

• Entry DOI: 10.2210/pdb9n5r/pdb
• Descriptor: 3C-like proteinase, (4S)-2-METHYL-2,4-PENTANEDIOL, N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-[(propan-2-yl)oxy]-L-prolinamide, ... (4 entities in total)
• Functional Keywords: main protease, 3-chymotrypsin-like protease, mpro, 3clpro, structural genomics, center for structural biology of infectious diseases, csbid, viral protein
• Biological source: Canine coronavirus
• Total number of polymer chains: 2
• Total formula weight: 67594.55

Authors

Jayashankar, U.,Ghosh, A.K.,Mesecar, A.D.,Center for Structural Biology of Infectious Diseases (CSBID) (deposition date: 2025-02-04, release date: 2026-09-09)

• Primary citation: Jayashankar, U.,Ghosh, A.K.,Mesecar, A.D.; X-ray structure of CCoV-HuPn-2018 main protease covalently bound to inhibitor GRL-170-21 at 1.89A.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.89 Å)