9N44

Crystal structure of human KRAS-G12C covalent bound to Olomorasib

This is a non-PDB format compatible entry.

Summary for 9N44

• Entry DOI: 10.2210/pdb9n44/pdb
• Descriptor: Isoform 2B of GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: gtpase, kras-g12c, olomorasib, oncoprotein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 20480.42

Authors

Wang, J.,Hendle, J.,Saflor, M.D.,Lagutan, M.D.,Gheyi, T.,Sarkar, A.,Kearins, M.,Tung, F.,Ho, J.,Rodgers, L.,Benach, J.,Frommelt, A.J. (deposition date: 2025-02-01, release date: 2025-12-10)

• Primary citation: Wang, J.,Hendle, J.,Saflor, M.D.,Lagutan, M.D.,Gheyi, T.,Sarkar, A.,Kearins, M.,Tung, F.,Ho, J.,Rodgers, L.,Benach, J.,Frommelt, A.J.; Crystal structure of human KRAS-G12C covalent bound to Olomorasib; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.11 Å)