9MZF

Cryo-EM structure of GLP-1R-Gs complex with peptide 15

Summary for 9MZF

• Entry DOI: 10.2210/pdb9mzf/pdb
• EMDB information: 48755
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Nb35, ... (7 entities in total)
• Functional Keywords: gpcr, cryo-em, dual peptide agonist, complex, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 164740.48

Authors

Zhang, X.,Belousoff, J.M.,Wootten, D.,Sexton, M.P. (deposition date: 2025-01-22, release date: 2026-04-22)

• Primary citation: Zhang, X.,Belousoff, J.M.,Wootten, D.,Sexton, M.P.; Cryo-EM structure of GLP-1R-Gs complex with peptide 15; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.5 Å)