9MZE

Cryo-EM structure of GLP-1R-Gs complex with oxyntomodulin

Summary for 9MZE

• Entry DOI: 10.2210/pdb9mze/pdb
• EMDB information: 48754
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: gpcr, peptide agonist, membrane protein, cryo-em
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 165671.56

Authors

Zhang, X.,Belousoff, M.J.,Wootten, D.,Sexton, P.M. (deposition date: 2025-01-22, release date: 2026-04-22)

• Primary citation: Zhang, X.,Belousoff, M.J.,Wootten, D.,Sexton, P.M.; Cryo-EM structure of GLP-1R-Gs complex with oxyntomodulin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.2 Å)