9MYX

Structure of rat neuronal nitric oxide synthase R349A mutant heme domain bound with 7-(3-aminomethyl)phenyl-6-fluoro-4-methylquinoin-2-amine

This is a non-PDB format compatible entry.

Summary for 9MYX

• Entry DOI: 10.2210/pdb9myx/pdb
• Descriptor: Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (7 entities in total)
• Functional Keywords: nitric oxide synthase inhibitor binding, oxidoreductase-inhibitor complex, oxidoreductase
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 1
• Total formula weight: 49989.92

Authors

Li, H.,Poulos, T.L. (deposition date: 2025-01-22, release date: 2025-12-03)

• Primary citation: Ansari, A.,Rathnayake, A.D.,Li, H.,Hardy, C.D.,Poulos, T.L.,Silverman, R.B.; Design and synthesis of 7-aryl-6-fluoro-2-aminoquinolines as potent and highly selective human neuronal nitric oxide synthase inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.821 Å)