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9MWM

Structure of rat neuronal nitric oxide synthase R349A mutant heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)thiazole-5-carboximidamide

This is a non-PDB format compatible entry.
Summary for 9MWM
Entry DOI10.2210/pdb9mwm/pdb
DescriptorNitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (7 entities in total)
Functional Keywordsnitric oxide synthase inhibitor binding, oxidoreductase
Biological sourceRattus norvegicus (Norway rat)
Total number of polymer chains1
Total formula weight50150.19
Authors
Li, H.,Poulos, T.L. (deposition date: 2025-01-17, release date: 2025-11-26)
Primary citationAwasthi, A.,Li, H.,Hardy, C.D.,Poulos, T.L.,Silverman, R.B.
A step forward for neuronal Nitric Oxide Synthase Inhibitors against Melanoma
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

247536

PDB entries from 2026-01-14

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