9MWL

Structure of rat neuronal nitric oxide synthase R349A mutant heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)thiophene-2-carboximidamide

This is a non-PDB format compatible entry.

Summary for 9MWL

• Entry DOI: 10.2210/pdb9mwl/pdb
• Descriptor: Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (7 entities in total)
• Functional Keywords: nitric oxide synthase inhibitor binding, oxidoreductase
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 1
• Total formula weight: 50149.20

Authors

Li, H.,Poulos, T.L. (deposition date: 2025-01-17, release date: 2025-11-26)

• Primary citation: Awasthi, A.,Li, H.,Hardy, C.D.,Poulos, T.L.,Silverman, R.B.; A step forward for neuronal Nitric Oxide Synthase Inhibitors against Melanoma; To be published,

Experimental method

X-RAY DIFFRACTION (1.87 Å)