9MWA

Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain bound with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide

Summary for 9MWA

• Entry DOI: 10.2210/pdb9mwa/pdb
• Descriptor: Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (7 entities in total)
• Functional Keywords: nitric oxide synthase inhibitor binding, oxidoreductase-inhibitor complex, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 201939.96

Authors

Li, H.,Poulos, T.L. (deposition date: 2025-01-17, release date: 2025-11-26)

• Primary citation: Awasthi, A.,Li, H.,Hardy, C.D.,Poulos, T.L.,Silverman, R.B.; A step forward for neuronal Nitric Oxide Synthase Inhibitors against Melanoma; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)