9MVS

Activated Leptotrichia buccalis (Lbu) CRISPR-Cas13a bound to AI-designed anti-CRISPR AIcrVIA1

Summary for 9MVS

• Entry DOI: 10.2210/pdb9mvs/pdb
• EMDB information: 48668
• Descriptor: AIcrVIA1, CRISPR-associated endoribonuclease Cas13a, crRNA, ... (4 entities in total)
• Functional Keywords: crispr, acr, cas13, de novo, de novo protein, de novo protein-hydrolase-rna complex, de novo protein/hydrolase/rna
• Biological source: synthetic construct; More
• Total number of polymer chains: 4
• Total formula weight: 174953.23

Authors

Taveneau, C.,Knott, G.J. (deposition date: 2025-01-15, release date: 2026-02-25)

• Primary citation: Taveneau, C.,Chai, X.H.,D'Silva, J.,Bamert, R.S.,Hayes, B.K.,Calvert, R.W.,Curwen, D.J.,Munder, F.,Martin, L.L.,Barr, J.J.,Grinter, R.,Knott, G.J.; De novo design of potent CRISPR-Cas13 inhibitors; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.43 Å)