9MS8

PTCH1 in complex with Fab6H3

Summary for 9MS8

• Entry DOI: 10.2210/pdb9ms8/pdb
• EMDB information: 48568
• Descriptor: Protein patched homolog 1, 6H3 Fab light chain, 6H3 Fab heavy chain (3 entities in total)
• Functional Keywords: ptch1, antibody, hedgehog signaling, cryo-em, membrane protein., membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 145410.96

Authors

Hu, Q.,Qi, X.,Li, X. (deposition date: 2025-01-09, release date: 2025-04-02, Last modification date: 2025-04-16)

• Primary citation: Hu, Q.,Qi, X.,Donnelly, L.,Li, X.; Inhibiting hedgehog signal by a patched-1 antibody.; Cell Discov, 11:29-29, 2025; PubMed: 40128518; DOI: 10.1038/s41421-025-00772-6

Experimental method

ELECTRON MICROSCOPY (3.73 Å)