9MN0

E. coli SR1 single-ring GroEL templated into pseudo-double-ring complex with PBZ1587 inhibitor

This is a non-PDB format compatible entry.

Summary for 9MN0

• Entry DOI: 10.2210/pdb9mn0/pdb
• EMDB information: 48409
• Descriptor: Chaperonin GroEL, N-(2-{4-[4-(aminomethyl)benzene-1-sulfonamido]phenyl}-1,3-benzoxazol-5-yl)-5-chlorothiophene-2-sulfonamide (2 entities in total)
• Functional Keywords: chaperone inhibitor, chaperone
• Biological source: Escherichia coli
• Total number of polymer chains: 14
• Total formula weight: 805687.10

Authors

Johnson, S.M.,Chen, Q. (deposition date: 2024-12-20, release date: 2026-01-21)

• Primary citation: Stevens, M.,Doud, E.,Norambuena, J.,Tepper, K.,Trindl, C.A.,Carpenter, R.,Chapman, E.,Boyd, J.M.,Wells, C.,Chen, Q.,Johnson, S.M.; Deciphering the unique mechanism whereby bis-sulfonamido-2-phenylbenzoxazole (PBZ) GroEL/ES inhibitors modulate chaperonin ATPase and client protein folding functions.; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)