9MLX

Crosslinked complex of ketosynthase FabB mutant FabBG107M and acyl carrier protein AcpP from E.coli with C12 crosslinker

Summary for 9MLX

• Entry DOI: 10.2210/pdb9mlx/pdb
• Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, N-[2-(dodecanoylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... (4 entities in total)
• Functional Keywords: ketosynthase, acyl carrier protein, crosslinker, fatty acid biosynthesis, short chain fatty acid, fabb, acpp, acp, protein engineering, biosynthetic protein, transferase
• Biological source: Escherichia coli str. K-12 substr. MG1655; More
• Total number of polymer chains: 4
• Total formula weight: 103242.12

Authors

Jiang, Z.,Sankaran, B.,Burkart, M.D.,Fox, J.M. (deposition date: 2024-12-19, release date: 2026-10-14)

• Primary citation: Jiang, Z.,Friedman, A.J.,Thompson, A.,Andrzejewski, S.,Mains, K.M.,Sankaran, B.,Burkart, M.D.,Fox, M.F.; Biomolecular Plasticity Permits Diverse Product Profiles in Ketosynthase Mutants; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)