9MHP

cryo-EM structure of full-length and internally HIS-tagged yeast E3 ubiquitin ligase Tom1p, in a closed-conformation state with helical repeat solenoid architecture

Summary for 9MHP

• Entry DOI: 10.2210/pdb9mhp/pdb
• EMDB information: 48280
• Descriptor: E3 ubiquitin-protein ligase TOM1 (1 entity in total)
• Functional Keywords: cell cycle, stress response, solenoid, e3 ubiquitin ligase, rna, gene regulation
• Biological source: Saccharomyces cerevisiae (brewer's yeast)
• Total number of polymer chains: 1
• Total formula weight: 376741.59

Authors

Madrigal, J.A.,Schubert, H.L. (deposition date: 2024-12-12, release date: 2025-10-01)

• Primary citation: Madrigal, J.A.,Schubert, H.L.,Sdano, M.A.,McCullough, L.,Connell, Z.,Formosa, T.G.,Hill, C.P.; Tom1p ubiquitin ligase structure, interaction with Spt6p, and function in maintaining normal transcript levels and the stability of chromatin in promoters; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.97 Å)