9MC0

The co-crystal structure of DYRK2 with AF-4

This is a non-PDB format compatible entry.

Summary for 9MC0

• Entry DOI: 10.2210/pdb9mc0/pdb
• Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2-[[4-(1,3-benzothiazol-5-yl)-5-fluoranyl-pyrimidin-2-yl]amino]-1,3-thiazol-5-yl]-piperazin-1-yl-methanone (2 entities in total)
• Functional Keywords: inhibitor, cell cycle
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 90193.96

Authors

Shen, H.T.,Xiao, Y.B. (deposition date: 2025-03-17, release date: 2026-03-25)

• Primary citation: Shen, H.T.,Xiao, Y.B.; Targeting DYRK2 for the treatment of cancer; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.87 Å)