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9M8U

Cryo-EM structure of human SIDT1

Summary for 9M8U
Entry DOI10.2210/pdb9m8u/pdb
EMDB information63722
DescriptorIsoform 2 of SID1 transmembrane family member 1 (1 entity in total)
Functional Keywordsdimer, transport, membrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight188881.48
Authors
Liao, L.,Sun, L. (deposition date: 2025-03-12, release date: 2026-03-18)
Primary citationHu, T.,Han, Z.,Liao, L.,Zeng, Y.,Ma, H.,Huang, J.,Chen, Y.,Ye, J.,Zhou, T.,Zhang, W.,Cang, C.,Sun, L.,Pan, W.,Wang, J.,Zhu, S.
SIDT1 is a calcium-associated CD8+ T cell suppressor and target for cancer immunotherapy
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.79 Å)
Structure validation

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PDB entries from 2026-03-18

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