9M76

UHRF1 bound to a mononucleosome in its pre-active state, with the RING domain bound to the SRA domain.

Summary for 9M76

• Entry DOI: 10.2210/pdb9m76/pdb
• Related: 9M75
• EMDB information: 63676
• Descriptor: Histone H4, Histone H2A, Histone H2B 1.1, ... (8 entities in total)
• Functional Keywords: epigenetic reader/writer protein involved in dna methylation., dna binding protein
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 11
• Total formula weight: 288994.27

Authors

Naschberger, A.,Baradaran, R.,Sayed, A.,Fischle, W. (deposition date: 2025-03-09, release date: 2026-03-11)

• Primary citation: Naschberger, A.,Baradaran, R.,Sayed, A.,Fischle, W.; The cryo-EM structure of human UHRF1 bound to mononucleosomes.; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.1 Å)