9LYS

Crystal structure of de novo designed amantadine binding homotrimer dAIT03

Summary for 9LYS

• Entry DOI: 10.2210/pdb9lys/pdb
• Descriptor: dAIT03, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine (3 entities in total)
• Functional Keywords: drug binding homotrimer, de novo protein
• Biological source: Escherichia coli
• Total number of polymer chains: 3
• Total formula weight: 20163.53

Authors

Qihan, J.,Longxing, C. (deposition date: 2025-02-20, release date: 2025-12-17)

• Primary citation: Jin, Q.,Wang, Y.,Chen, D.,Liao, J.,Cui, Z.,Fan, Y.,Zeng, A.,Xie, M.,Cao, L.; De novo design of small molecule-regulated protein oligomers; Science, 2026; DOI: 10.1126/science.ady6017

Experimental method

X-RAY DIFFRACTION (2 Å)