9LXN

Human RNA Polymerase III de novo transcribing complex 5 (TC5)(without 3'dATP)

Summary for 9LXN

• Entry DOI: 10.2210/pdb9lxn/pdb
• EMDB information: 63482
• Descriptor: snRNA-activating protein complex subunit 1, DNA-directed RNA polymerase III subunit RPC8, DNA-directed RNA polymerases I, II, and III subunit RPABC3, ... (30 entities in total)
• Functional Keywords: initiation transcribing complex, transcription/dna/rna, transcription-dna-rna complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 26
• Total formula weight: 1417396.57

Authors

Wang, Q.,Ren, Y.,Jin, Q.,Chen, X.,Xu, Y. (deposition date: 2025-02-18, release date: 2025-04-16, Last modification date: 2025-06-11)

• Primary citation: Wang, Q.,Ren, Y.,Jin, Q.,Chen, X.,Xu, Y.; Structural insights into human Pol III transcription initiation in action; Nature, 2025; DOI: 10.1038/s41586-025-09093-w

Experimental method

ELECTRON MICROSCOPY (3.3 Å)