9LWI

The head region of HBx-Smc5/6 ubiquitination complex

Summary for 9LWI

• Entry DOI: 10.2210/pdb9lwi/pdb
• EMDB information: 63446
• Descriptor: Structural maintenance of chromosomes protein 6, ZINC ION, DNA damage-binding protein 1, ... (10 entities in total)
• Functional Keywords: hbx, smc5/6, cul4a-rbx, hbv, antiviral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 603261.80

Authors

Tong, C.,Lili, D.,Hongshuai, L.,Jinhong, Z.,Qian, X.,Lanfeng, W. (deposition date: 2025-02-15, release date: 2026-04-29)

• Primary citation: Cheng, T.,Zhou, J.,Huang, W.,Du, L.,He, P.,Yang, R.,Gao, Y.,Hao, M.,Hu, K.,Chen, J.,Wang, H.,Rao, Z.,Yuan, Z.,Wang, L.; Structural and functional insights into HBx-Smc6 targeting for HBV inhibition.; Cell Res., 2026; PubMed: 41991645; DOI: 10.1038/s41422-026-01251-7

Experimental method

ELECTRON MICROSCOPY (3.12 Å)