9LSZ

Inward-open Structure of human B0AT1

Summary for 9LSZ

• Entry DOI: 10.2210/pdb9lsz/pdb
• EMDB information: 63360
• Descriptor: Sodium-dependent neutral amino acid transporter B(0)AT1, Antibody Fab Light chain, Antibody Fab Heavy chain, ... (4 entities in total)
• Functional Keywords: amino acid transporter, slc6, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 130668.66

Authors

Imazu, T.,Miyaguchi, I.,Hiraizumi, M. (deposition date: 2025-02-05, release date: 2026-02-18)

• Primary citation: Imazu, T.,Akashi, T.,Hiraizumi, M.,Inui, Y.,Sasaki, W.,Takahashi, T.,Todoroki, H.,Kumanomidou, T.,Hisano, H.,Asada, H.,Kusakizako, T.,Nishizawa, T.,Iwata, S.,Nureki, O.,Miyaguchi, I.; Structure-guided development of a potent human B0AT1 inhibitor effective in a mouse model of phenylketonuria; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.11 Å)